2196245-16-4
Chemical Structure
Lp-PLA2-IN-3
- CAS No.: 2196245-16-4
- Formula:C20H13ClF3N3O3S
- Molecular Weight:467.85
IUPAC Name: 4-amino-N-(4-(4-chloro-3-(trifluoromethyl)phenoxy)-3-cyanophenyl)benzenesulfonamide
InChIKey: GADGQEKPNKSGMT-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(N)C=C1)(NC2=CC=C(OC3=CC=C(Cl)C(C(F)(F)F)=C3)C(C#N)=C2)=O
Biological Activity: Lp-PLA2-IN-3 is a potent and orally bioavailable lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 14 nM for recombinant human Lp-PLA2 (rhLpPLA2)[1].
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Lp-PLA2-IN-3 | 99.94% | Lp-PLA2-IN-3 is a potent and orally bioavailable lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 14 nM for recombinant human Lp-PLA2 (rhLpPLA2). | ||||||||||||||||||||
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Keywords