22144-76-9
22144-76-9
Chemical Structure
Cytochalasin C
- CAS No.: 22144-76-9
- Formula:C30H37NO6
- Molecular Weight:507.62
IUPAC Name: (3S,3aR,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,5,10,12-tetramethyl-1,11-dioxo-2,3,3a,6,6a,9,10,11,12,15-decahydro-1H-cycloundeca[d]isoindol-15-yl acetate
InChIKey: NAIODHJWOHMDJX-FLMVKAFASA-N
SMILES: CC1=C(C)[C@@H](O)[C@@](/C=C/C[C@@H]2C)([H])[C@](C(N[C@H]3CC4=CC=CC=C4)=O)([C@]31[H])[C@H](OC(C)=O)/C=C/[C@](O)(C)C2=O
Biological Activity: Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cytochalasin C | 99.85% | Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D. | ||||||||||||||||||||
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References
- [1]. Foissner I, et al. Wide-ranging effects of eight cytochalasins and latrunculin A and B on intracellular motility and actin filament reorganization in characean internodal cells. Plant Cell Physiol. 2007 Apr;48(4):585-97. [Content Brief]
- [2]. Yahara I, et al. Correlation between effects of 24 different cytochalasins on cellular structures and cellular eventsand those on actin in vitro. J Cell Biol. 1982 Jan;92(1):69-78. [Content Brief]
- [3]. Trendowski M, et al. Tolerated doses in zebrafish of cytochalasins and jasplakinolide for comparison with tolerateddoses in mice in the evaluation of pre-clinical activity of microfilament-directed agents in tumormodel systems in vivo. In Vivo. 2014 Nov-D [Content Brief]
