22994-85-0
22994-85-0
Chemical Structure
Benznidazole
Synonym(s): Benznidazol; Ro 07-1051; Ro 71051
- CAS No.: 22994-85-0
- Formula:C12H12N4O3
- Molecular Weight:260.25
IUPAC Name: N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide
InChIKey: CULUWZNBISUWAS-UHFFFAOYSA-N
SMILES: O=C(NCC1=CC=CC=C1)CN2C=CN=C2[N+]([O-])=O
Biological Activity: Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease[1][2].
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Benznidazole | 99.90% | Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease. | ||||||||||||||||||||
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Benznidazole (Standard) | ≥98% | Benznidazole (Standard) is the analytical standard of Benznidazole. This product is intended for research and analytical applications. Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease. | ||||||||||||||||||||
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Benznidazole-d7 | Benznidazole-d7 (Benznidazol-d7; Ro 07-1051-d7; Ro 71051-d7) is the deuterium labeled Benznidazole (HY-B1548). Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease. | |||||||||||||||||||||
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References
- [1]. Bustamante JM, et al. Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy. Int J Antimicrob Agents. 2007 Jun;29(6):733-7. [Content Brief]
- [2]. Luna KP, et al. In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. Biomedica. 2009 Sep;29(3):448-55. [Content Brief]
