2305045-76-3
2305045-76-3
Chemical Structure
XL 188
- CAS No.: 2305045-76-3
- Formula:C32H42N6O4
- Molecular Weight:574.71
IUPAC Name: (R)-N-(3-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-4-oxo-3,4-dihydroquinazolin-7-yl)-3-(4-methylpiperazin-1-yl)propanamide
InChIKey: QLBYDWATOPNXBG-XMMPIXPASA-N
SMILES: O=C(NC1=CC(N=CN2CC3(O)CCN(C(C[C@H](C4=CC=CC=C4)C)=O)CC3)=C(C=C1)C2=O)CCN5CCN(C)CC5
Biological Activity: XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively. XL 188 can be used in research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XL 188 | 99.21% | XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively. XL 188 can be used in research of cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.74
HY-160515USP7-IN-13 -
Similarity Score 0.63
HY-16709USP7-IN-1 -
Similarity Score 0.59
HY-138794XL177A -
Similarity Score 0.59
HY-138794A(Rac)-XL177A -
Similarity Score 0.59
HY-138794BXL177B -
Similarity Score 0.58
HY-183942USP7-IN-20 -
Similarity Score 0.57
HY-122646USP7-IN-2 -
Similarity Score 0.57
HY-160502CST967 -
Similarity Score 0.54
HY-175360USP7 Ligand-Linker Conjugates 1 -
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