2305052-86-0
2305052-86-0
Chemical Structure
BPK-25
- CAS. Nr.: 2305052-86-0
- Formula:C21H17ClN4O2
- Molecular Weight:392.84
IUPAC Name: 5-(N-((6-chloropyridin-2-yl)methyl)acrylamido)-N-phenylpicolinamide
InChIKey: MHPBTJANPDDCPH-UHFFFAOYSA-N
SMILES: O=C(N(CC1=NC(Cl)=CC=C1)C2=CN=C(C(NC3=CC=CC=C3)=O)C=C2)C=C
Biological Activity: BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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BPK-25 | 99.88% | BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP. | ||||||||||||||||||||
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References
Keywords
