2305052-86-0
2305052-86-0
Chemical Structure
BPK-25
- CAS No.: 2305052-86-0
- Formula:C21H17ClN4O2
- Molecular Weight:392.84
IUPAC Name: 5-(N-((6-chloropyridin-2-yl)methyl)acrylamido)-N-phenylpicolinamide
InChIKey: MHPBTJANPDDCPH-UHFFFAOYSA-N
SMILES: O=C(N(CC1=NC(Cl)=CC=C1)C2=CN=C(C(NC3=CC=CC=C3)=O)C=C2)C=C
Biological Activity: BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BPK-25 | 99.54% | BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.53
HY-W112115N2,N6-Di(pyridin-3-yl)pyridine-2,6-dicarboxamide -
Similarity Score 0.53
HY-117450VU0415374 -
Similarity Score 0.52
HY-152174HDAC-IN-52 -
Similarity Score 0.51
HY-184177W2A-28 -
Similarity Score 0.51
HY-114146CID 1375606 -
Similarity Score 0.50
HY-163764Bfl-1-IN-4 -
Similarity Score 0.50
HY-W243994N2,N6-Bis(pyridin-2-ylmethyl)pyridine-2,6-dicarboxamide -
Similarity Score 0.50
HY-152173HDAC-IN-51 -
Similarity Score 0.50
HY-110190VU0422288 -
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