232935-92-1
232935-92-1
Chemical Structure
WX8
Synonym(s): Ro 91-4714
- CAS No.: 232935-92-1
- Formula:C22H22N8O
- Molecular Weight:414.46
InChIKey: NJIKLALXAPYTCW-BUVRLJJBSA-N
SMILES: C1(/C=N/NC2=NC(NC3=CC=CC=C3)=NC(N4CCOCC4)=N2)=CNC5=C1C=CC=C5
Biological Activity: WX8 (Ro 91-4714) is an ATP-competitive PIKFYVE inhibitor, with Kd values of 0.9 nM and 340 nM for PIKFYVE and PIP4K2C, respectively. WX8 (Ro 91-4714) inhibits lysosomal fission without effecting homotypic lysosomal fusion. WX8 (Ro 91-4714) is used in the research of autophagy-dependent cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WX8 | 99.43% | WX8 (Ro 91-4714) is an ATP-competitive PIKFYVE inhibitor, with Kd values of 0.9 nM and 340 nM for PIKFYVE and PIP4K2C, respectively. WX8 (Ro 91-4714) inhibits lysosomal fission without effecting homotypic lysosomal fusion. WX8 (Ro 91-4714) is used in the research of autophagy-dependent cancer. | ||||||||||||||||||||
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References
Keywords
