23758-16-9
23758-16-9
Chemical Structure
Scandenolide
- CAS No.: 23758-16-9
- Formula:C17H18O7
- Molecular Weight:334.32
IUPAC Name: (4R,8R,9aS,10aS,11aS,Z)-10a-methyl-3-methylene-2,6-dioxo-2,3,3a,4,8,9,9a,10a,11,11a-decahydro-6H-4,7-(metheno)furo[3,2-c]oxireno[2,3-f][1]oxacycloundecin-8-yl acetate
InChIKey: SLIMCFUYVZKJTC-IANRCNAMSA-N
SMILES: O=C1C2=C[C@@H](O1)C(C(C(O3)=O)=C)[C@@H]3C[C@@]4(C)[C@@H](O4)C[C@H]2OC(C)=O
Biological Activity: Scandenolide is a sesquiterpene lactone that can be found in Philippines medicinal plant Mikania cordata. Scandenolide inhibits leukotriene and platelet activating factor synthesis in leukocytes[1][2].
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Scandenolide | Scandenolide is a sesquiterpene lactone that can be found in Philippines medicinal plant Mikania cordata. Scandenolide inhibits leukotriene and platelet activating factor synthesis in leukocytes. | |||||||||||||||||||||
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References
- [1]. Ahmed M, et ,al. Analgesic sesquiterpene dilactone from Mikania cordata. Fitoterapia. 2001 Dec;72(8):919-21. [Content Brief]
- [2]. Ysrael MC, et, al. Inhibition of leukotriene and platelet activating factor synthesis in leukocytes by the sesquiterpene lactone scandenolide. Planta Med. 1990 Jun;56(3):268-70. [Content Brief]
