2378159-28-3
2378159-28-3
Chemical Structure
PAR2 modulator-1
- CAS No.: 2378159-28-3
- Formula:C27H41N5O5
- Molecular Weight:515.64
InChIKey: PMKXCZFRNZTXJG-GAIPOIILSA-N
SMILES: O=C(C1=CC=CO1)N2C3N(C([C@H](C2)NC(CC(C)C)=O)=O)[C@H](C(N(C3)CC4CCNCC4)=O)CC(C)C
Biological Activity: PAR2 modulator-1 is a biased protease-activated receptor 2 (PAR2) inhibitor. PAR2 modulator-1 blocks the PAR2-dependent MAPK signaling pathway with an IC50 value of 8.5 μM, without altering the PAR2-dependent Ca2+ signaling pathway. PAR2 modulator-1 blocks pain responses induced by PAR2 agonists. PAR2 modulator-1 can be used in the research of chronic pain[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PAR2 modulator-1 | 98.93% | PAR2 modulator-1 is a biased protease-activated receptor 2 (PAR2) inhibitor. PAR2 modulator-1 blocks the PAR2-dependent MAPK signaling pathway with an IC50 value of 8.5 μM, without altering the PAR2-dependent Ca2+ signaling pathway. PAR2 modulator-1 blocks pain responses induced by PAR2 agonists. PAR2 modulator-1 can be used in the research of chronic pain. | ||||||||||||||||||||
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