2396592-52-0
Chemical Structure
SARM1-IN-2
- CAS 番号: 2396592-52-0
- Formula:C16H14N4O2S
- Molecular Weight:326.37
IUPAC Name: 5-((6-methoxy-2-methylquinolin-5-yl)amino)-2-methyl-3-oxo-2,3-dihydroisothiazole-4-carbonitrile
InChIKey: YCKJOVSJCNUPNR-UHFFFAOYSA-N
SMILES: N#CC1=C(NC2=C3C=CC(C)=NC3=CC=C2OC)SN(C)C1=O
Biological Activity: SARM1-IN-2 (Example 82) is a SARM1 inhibitor (IC50 <1 μM) that inhibits axon regeneration. Axon regeneration refers to the process by which neuronal axons attempt to restore their structure and function after axonal degeneration. SARM1-IN-2 inhibits axon regeneration by reducing or inhibiting the binding of SARM1 to NAD+. SARM1-IN-2 can be used to study axonal degeneration[1][2].
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SARM1-IN-2 | 99.97% | SARM1-IN-2 (Example 82) is a SARM1 inhibitor (IC50 <1 μM) that inhibits axon regeneration. Axon regeneration refers to the process by which neuronal axons attempt to restore their structure and function after axonal degeneration. SARM1-IN-2 inhibits axon regeneration by reducing or inhibiting the binding of SARM1 to NAD+. SARM1-IN-2 can be used to study axonal degeneration. | ||||||||||||||||||||
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