SARM1-IN-2
Based on 1 Customer Validation
SARM1-IN-2 (Example 82) is a SARM1 inhibitor (IC50 <1 μM) that inhibits axon regeneration. Axon regeneration refers to the process by which neuronal axons attempt to restore their structure and function after axonal degeneration. SARM1-IN-2 inhibits axon regeneration by reducing or inhibiting the binding of SARM1 to NAD+. SARM1-IN-2 can be used to study axonal degeneration.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 2396592-52-0
- Formula: C16H14N4O2S
- Molecular Weight:326.37
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
SARM1-IN-2 treatment resulted in only 6% axon regeneration after 72 hours[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2396592-52-0
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Appearance Solid
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Molecular Weight 326.37
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Formula C16H14N4O2S
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Color Light yellow to yellow
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SMILES
N#CC1=C(NC2=C3C=CC(C)=NC3=CC=C2OC)SN(C)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 10 mg/mL (30.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0640 mL | 15.3200 mL | 30.6401 mL | 76.6002 mL |
| 5 mM | 0.6128 mL | 3.0640 mL | 6.1280 mL | 15.3200 mL | |
| 10 mM | 0.3064 mL | 1.5320 mL | 3.0640 mL | 7.6600 mL | |
| 15 mM | 0.2043 mL | 1.0213 mL | 2.0427 mL | 5.1067 mL | |
| 20 mM | 0.1532 mL | 0.7660 mL | 1.5320 mL | 3.8300 mL | |
| 25 mM | 0.1226 mL | 0.6128 mL | 1.2256 mL | 3.0640 mL | |
| 30 mM | 0.1021 mL | 0.5107 mL | 1.0213 mL | 2.5533 mL |
SARM1-IN-2 Related Classifications
HY-145917 Related Classifications
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