2407654-51-5
2407654-51-5
Chemical Structure
ZXH-1-161
- CAS No.: 2407654-51-5
- Formula:C26H24N6O3
- Molecular Weight:468.51
IUPAC Name: 3-(4-((2-((2,3-dihydro-1H-inden-5-yl)amino)pyrimidin-4-yl)amino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
InChIKey: KCIIVRZRNLZKQA-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=C(C2)C(NC4=NC(NC5=CC=C6C(CCC6)=C5)=NC=C4)=CC=C3)=O)=O
Biological Activity: ZXH-1-161 is a potent CRBN modulator that selectively induces the degradation of GSPT1 in a CRBN-dependent manner. ZXH-1-161 can inhibit the proliferation of multiple myeloma cells and exhibits antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ZXH-1-161 | 98.43% | ZXH-1-161 is a potent CRBN modulator that selectively induces the degradation of GSPT1 in a CRBN-dependent manner. ZXH-1-161 can inhibit the proliferation of multiple myeloma cells and exhibits antitumor activity. | ||||||||||||||||||||
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References
Keywords
