2493976-27-3
2493976-27-3
Chemical Structure
Dyrk1A-IN-3
- CAS No.: 2493976-27-3
- Formula:C18H16N6
- Molecular Weight:316.36
IUPAC Name: N-methyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)-N-(m-tolyl)pyrimidin-2-amine
InChIKey: XOBINHQHMGZFDI-UHFFFAOYSA-N
SMILES: CC1=CC(N(C)C2=NC(C3=C4C=CC=NN4N=C3)=CC=N2)=CC=C1
Biological Activity: Dyrk1A-IN-3 (Compound 8b), a highly selective dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease[1].
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Dyrk1A-IN-3 | 99.68% | Dyrk1A-IN-3 (Compound 8b), a highly selective dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease. | ||||||||||||||||||||
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