1. Protein Tyrosine Kinase/RTK
  2. DYRK
  3. AZ-Dyrk1B-33

AZ-Dyrk1B-33 

Cat. No.: HY-117391 Purity: >99.0%
Handling Instructions

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor, with an IC50 of 7 nM.

For research use only. We do not sell to patients.

AZ-Dyrk1B-33 Chemical Structure

AZ-Dyrk1B-33 Chemical Structure

CAS No. : 1679330-37-0

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor, with an IC50 of 7 nM[1].

IC50 & Target

IC50: 7 nM (Dyrk1B)[1]

In Vitro

AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM[1].
AZ-Dyrk1B-33 shows no effect in sensitization[1].

Molecular Weight

300.36

Formula

C₁₉H₁₆N₄

CAS No.

1679330-37-0

SMILES

CC1=NC=CC(C2=CN(CC3=CC=CC=C3)C4=C2C=CN=C4)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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Keywords:

AZ-Dyrk1B-33DYRKDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseMirk-relatedMinibrain-relatedkinaseDyrk1BosteosarcomametabolicsyndromeresistancemechanismcellsundergoingastressresponseInhibitorinhibitorinhibit

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AZ-Dyrk1B-33
Cat. No.:
HY-117391
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