2. Anti-infection Cell Cycle/DNA Damage Stem Cell/Wnt PI3K/Akt/mTOR
  3. Parasite CDK GSK-3
  4. Antitrypanosomal agent 31

Antitrypanosomal agent 31 is an antitrypanosoma agent with a pEC50 of 6.4. Antitrypanosomal agent 31 inhibits GSK-3β, CDK-2, and CDK-4 with pIC50s of 5.8, 6.9, and 7.1, respectively. Antitrypanosomal agent 31 can be used for the research of human african trypanosomiasis.

For research use only. We do not sell to patients.

Antitrypanosomal agent 31

Antitrypanosomal agent 31 Chemical Structure

CAS No. : 551919-54-1

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Antitrypanosomal agent 31 Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85 CDK10 CDK15 CDK17 CDK18 CDK20 PITSLRE

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GSK-3 GSK-3α GSK-3β

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Description

Antitrypanosomal agent 31 is an antitrypanosoma agent with a pEC50 of 6.4. Antitrypanosomal agent 31 inhibits GSK-3β, CDK-2, and CDK-4 with pIC50s of 5.8, 6.9, and 7.1, respectively. Antitrypanosomal agent 31 can be used for the research of human african trypanosomiasis[1].

IC50 & Target[1]

Trypanosoma

6.4 (pEC50)

human CDK2

6.9 (pIC50)

human CDK4

7.1 (pIC50)

GSK-3β

5.8 (pIC50)

In Vitro

Antitrypanosomal agent 31 (Compound 10c) inhibits Trypanosoma brucei growth with a pEC50 of 6.4, while also inhibiting human CDK-2, CDK-4, and GSK-3β kinases with pIC50s of 5.8, 6.9, and 7.1, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antitrypanosomal agent 31 Related Antibodies
Molecular Weight

252.28

Formula

C13H12N6
CAS No.
SMILES

N1=CC=C(N=C1NC2CC2)C=3C=NN4N=CC=CC34
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Purity & Documentation
References
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Antitrypanosomal agent 31 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitrypanosomal agent 31551919-54-1Antitrypanosomal agent31Antitrypanosomal agent-31ParasiteCDKGSK-3Cyclin dependent kinaseGlycogen synthase kinase-3Glycogen synthase kinase 3Trypanosoma brucei bruceiCDK-2GSK-3βhuman african trypanosomiasisCDK-4Inhibitorinhibitorinhibit

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