25129-91-3
Chemical Structure
Albocycline
Synonym(s): Ingramycin
- CAS No.: 25129-91-3
- Formula:C18H28O4
- Molecular Weight:308.41
IUPAC Name: (3E,5R,6E,8S,9E,13S,14R)-5-hydroxy-8-methoxy-5,9,13,14-tetramethyloxacyclotetradeca-3,6,9-trien-2-one
InChIKey: BYWWNDLILWPPJP-REXWONOSSA-N
SMILES: O=C1O[C@H](C)[C@@H](C)CC/C=C(C)/[C@@H](OC)/C=C/[C@@](C)(O)/C=C/1
Biological Activity: Albocycline (Ingramycin) is a macrolide antibiotic, which exhibits antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin (HY-B0671)-intermediate (VISA), and Vancomycin (HY-B0671)-resistant S. aureus (VRSA) strains with MICs ranging from 0.5 to 1.0 μg/mL. Albocycline exhibits no toxicity to human cells at concentration of ≤64 μg/mL[1].
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Albocycline | Albocycline (Ingramycin) is a macrolide antibiotic, which exhibits antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin (HY-B0671)-intermediate (VISA), and Vancomycin (HY-B0671)-resistant S. aureus (VRSA) strains with MICs ranging from 0.5 to 1.0 μg/mL. Albocycline exhibits no toxicity to human cells at concentration of ≤64 μg/mL. | |||||||||||||||||||||
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