257277-05-7
Chemical Structure
Iseganan
Synonym(s): IB-367
- CAS No.: 257277-05-7
- Formula:C78H126N30O18S4
- Molecular Weight:1900.28
SMILES: O=C(N[C@]1([H])C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N2)=O)NC([C@H](CC(C)C)NC(CNC(CNC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)C(C)C)=O)([H])CSSC1)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)[C@@H]2CC4=CC=C(C=C4)O
Biological Activity: Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Iseganan | 98.74% | Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.90
HY-P1633Protegrin-1 -
Similarity Score 0.69
![[Ala17]-MCH Chemical Structure](//file.medchemexpress.com/product_pic/hy-p1204.gif)
HY-P1204[Ala17]-MCH -
Similarity Score 0.69
HY-P5756CSD-CH2(1,8)-NH2 -
Similarity Score 0.68
HY-P5907Helianorphin-19 -
Similarity Score 0.67
HY-P11210A68828 -
Similarity Score 0.67
HY-P1102TC14012 -
Similarity Score 0.67
HY-P3155Ac-hMCH(6-16)-NH2 -
Similarity Score 0.66
![ANP [Des18-22] 4-23 amide (rat) Chemical Structure](//file.medchemexpress.com/product_pic/hy-p1526.gif)
HY-P1526ANP [Des18-22] 4-23 amide (rat) -
Similarity Score 0.66
HY-131374TN14003 -
Explore the MedChemAI to find more analogs
![[Ala17]-MCH Chemical Structure](http://file.medchemexpress.com/product_pic/hy-p1204.gif)
![ANP [Des18-22] 4-23 amide (rat) Chemical Structure](http://file.medchemexpress.com/product_pic/hy-p1526.gif)
References
- [1]. Toney JH. Iseganan (IntraBiotics pharmaceuticals). Curr Opin Investig Drugs. 2002 Feb;3(2):225-8. [Content Brief]
- [2]. Giles FJ, et al. Iseganan HCl: a novel antimicrobial agent. Expert Opin Investig Drugs. 2002 Aug;11(8):1161-70. [Content Brief]
- [3]. Landa A, et al. Antimicrobial peptides (Temporin A and Iseganan IB-367): effect on the cysticerci of Taenia crassiceps. Mol Biochem Parasitol. 2009 Apr;164(2):126-30. [Content Brief]
