2606-90-8
Chemical Structure
Thiamine diphosphate analog 1
- CAS No.: 2606-90-8
- Formula:C6H11NO7P2S
- Molecular Weight:303.17
IUPAC Name: 2-(4-methylthiazol-5-yl)ethyl trihydrogen diphosphate
InChIKey: UFUUMZHATZTWCW-UHFFFAOYSA-N
SMILES: O=P(O)(OP(O)(O)=O)OCCC1=C(C)N=CS1
Biological Activity: Thiamine diphosphate analog 1 is an analog of thiamine diphosphate. Thiamine diphosphate is the active metabolite of vitamin B1 in organisms. Thiamine diphosphate targets ThDP-dependent enzymes such as transketolase and pyruvate dehydrogenase complex, acting as an essential coenzyme to exert an activating effect. Thiamine diphosphate assists in catalytic reactions in free form and initiates the catalytic cycles of various glucose-metabolizing enzymes. Thiamine diphosphate serves as a diagnostic biomarker and protective factor for Alzheimer's disease. Thiamine diphosphate can be used in research related to metabolism and Alzheimer's disease[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Thiamine diphosphate analog 1 | Thiamine diphosphate analog 1 is an analog of thiamine diphosphate. Thiamine diphosphate is the active metabolite of vitamin B1 in organisms. Thiamine diphosphate targets ThDP-dependent enzymes such as transketolase and pyruvate dehydrogenase complex, acting as an essential coenzyme to exert an activating effect. Thiamine diphosphate assists in catalytic reactions in free form and initiates the catalytic cycles of various glucose-metabolizing enzymes. Thiamine diphosphate serves as a diagnostic biomarker and protective factor for Alzheimer's disease. Thiamine diphosphate can be used in research related to metabolism and Alzheimer's disease. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Kern D, et al. How Thiamine Diphosphate Is Activated in Enzymes. Science. 1997 Jan 3;275(5296):67-70.
- [2]. Duggleby RG, et al. Domain relationships in thiamine diphosphate-dependent enzymes. Acc Chem Res. 2006;39(8):550-557. [Content Brief]
- [3]. Wang C, et al. High thiamine diphosphate level as a protective factor for Alzheimer's disease. Neurol Res. 2018;40(8):658-665. [Content Brief]
Keywords
