2652579-44-5
2652579-44-5
Chemical Structure
HDAC2-IN-3
- CAS No.: 2652579-44-5
- Formula:C19H16N6OS
- Molecular Weight:376.43
InChIKey: VRAYULRGMAPDBT-UHFFFAOYSA-N
SMILES: NC1=CC=C(C=C1NC(C2=CN=C(C=N2)C3=CN(N=C3)C)=O)C4=CC=CS4
Biological Activity: HDAC2-IN-3 is a selective, orally active, blood-brain barrier permeable HDAC2 inhibitor with an IC50 of 14 nM. HDAC2-IN-3 upregulates histone acetylation levels in cells and in vivo, and enhances long-term potentiation (LTP) in the hippocampus. HDAC2-IN-3 can be used for the research of Alzheimer's disease[1].
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HDAC2-IN-3 | HDAC2-IN-3 is a selective, orally active, blood-brain barrier permeable HDAC2 inhibitor with an IC50 of 14 nM. HDAC2-IN-3 upregulates histone acetylation levels in cells and in vivo, and enhances long-term potentiation (LTP) in the hippocampus. HDAC2-IN-3 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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