26530-26-7
26530-26-7
Chemical Structure
KM04416
- CAS No.: 26530-26-7
- Formula:C12H11NO3S
- Molecular Weight:249.29
IUPAC Name: ethyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate
InChIKey: BZBRYBISKLKJCA-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=CC=C(N2SC=CC2=O)C=C1
Biological Activity: KM04416, an isothiazolone derivative, is a potent glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. KM04416 significantly inhibits PNT1A cell proliferation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
KM04416 | 98.76% | KM04416, an isothiazolone derivative, is a potent glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. KM04416 significantly inhibits PNT1A cell proliferation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.65
![Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate Chemical Structure](//file.medchemexpress.com/product_pic/hy-w140616.gif)
HY-W140616Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate -
Similarity Score 0.63
HY-77779Ethyl 4-(piperazin-1-yl)benzoate -
Similarity Score 0.62
HY-W111830Diethyl terephthalate -
Similarity Score 0.61
HY-121009CCT077791 -
Similarity Score 0.61
HY-W013482Benzyl 4-hydroxybenzoate -
Similarity Score 0.61
HY-W747060Benzyl 4-hydroxybenzoate-13C6 -
Similarity Score 0.61
HY-Z1081Monobenzyl Terephthalate -
Similarity Score 0.59
HY-N2269p-Hydroxyphenethyl anisate -
Similarity Score 0.59
HY-128854RDimethyl biphenyl-4,4'-dicarboxylate (Standard) -
Explore the MedChemAI to find more analogs
![Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w140616.gif)
References
- [1]. Sehyun Oh, et al. Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression. Theranostics. 2023 Jan 1;13(2):438-457. [Content Brief]
- [2]. Gurmit Singh, et al. Mitochondrial FAD-linked Glycerol-3-phosphate Dehydrogenase: A Target for Cancer Therapeutics. Pharmaceuticals (Basel). 2014 Feb 11;7(2):192-206. [Content Brief]
