2677039-24-4
2677039-24-4
Chemical Structure
BET BD2-IN-1
- CAS No.: 2677039-24-4
- Formula:C30H30N4O2
- Molecular Weight:478.58
InChIKey: GVCFSBGCJBRHFS-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC(CN2C3=C(C=C4C5=C2C=CC=C5C(N4C)=O)C=CC=C3)=C1)NC6CCN(CC6)C
Biological Activity: BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research[1].
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BET BD2-IN-1 | BET BD2-IN-1 (compound 45) is a potent and selective inhibitor of BET BD2 (IC50=1.6 nM). BET BD2-IN-1 inhibits the differentiation of Th17 cells by decreasing the activation of STAT3 and NF-κB. BET BD2-IN-1 is used in psoriasis and inflammatory bowel disease (IBD) research. | |||||||||||||||||||||
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References
Keywords
