2733575-91-0
2733575-91-0
Chemical Structure
Tagtociclib hydrate
Synonym(s): PF-07104091 hydrate
- CAS No.: 2733575-91-0
- Formula:C19H30N6O5
- Molecular Weight:422.48
IUPAC Name: (1R,3S)-3-(3-(3-(methoxymethyl)-1-methyl-1H-pyrazole-5-carboxamido)-1H-pyrazol-5-yl)cyclopentyl isopropylcarbamate hydrate
InChIKey: CFGMPDNYFGKCIR-DSHXVJGRSA-N
SMILES: O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2.[H]O[H]
Biological Activity: PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tagtociclib hydrate | 99.73% | PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2). | ||||||||||||||||||||
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Tagtociclib hydrate (Standard) | ≥98% | Tagtociclib hydrate (Standard) is the analytical standard of Tagtociclib hydrate (HY-137894A). This product is intended for research and analytical applications. PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2). | ||||||||||||||||||||
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