2733575-91-0

Tagtociclib hydrate Chemical Structure
2733575-91-0

Chemical Structure

Tagtociclib hydrate

Synonym(s): PF-07104091 hydrate

  • CAS No.: 2733575-91-0
  • Formula:C19H30N6O5
  • Molecular Weight:422.48

IUPAC Name: (1R,3S)-3-(3-(3-(methoxymethyl)-1-methyl-1H-pyrazole-5-carboxamido)-1H-pyrazol-5-yl)cyclopentyl isopropylcarbamate hydrate

InChIKey: CFGMPDNYFGKCIR-DSHXVJGRSA-N

SMILES: O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2.[H]O[H]

Biological Activity: PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).

Cat. No. Product Name Purity Description Pricing
HY-137894A 		Tagtociclib hydrate 99.73% PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).
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HY-137894AR 		Tagtociclib hydrate (Standard) 99.84% Tagtociclib hydrate (Standard) is the analytical standard of Tagtociclib hydrate (HY-137894A). This product is intended for research and analytical applications. PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).
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In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Pricing 
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Structural Analogs

Keywords