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Cat. No.: HY-150889

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CDK9 ligand 1

CDK9 ligand 1 is a CDK9-targeting ligand. CDK9 ligand 1 can be used for PROTAC synthesis, and serves as the target protein ligand for PROTAC CDK9 Degrader-1 (HY-103628).

For research use only. We do not sell to patients.

CAS No.: 2118356-94-6
Formula: C₁₆H₁₉N₃O₂
Molecular Weight:285.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK9 ligand 1 Chemical Structure

CAS No.: 2118356-94-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CDK9 ligand 1 is a CDK9-targeting ligand. CDK9 ligand 1 can be used for PROTAC synthesis, and serves as the target protein ligand for PROTAC CDK9 Degrader-1 (HY-103628)^[1].

IC₅₀ & Target^[1]

CDK9

All CDK Isoforms :

In Vitro

CDK9 ligand 1 serves as the target protein ligand for PROTAC CDK9 Degrader-1 (HY-103628), which degrades CDK9 in a dose-dependent manner in HCT116 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2118356-94-6
Molecular Weight 285.34
Formula C₁₆H₁₉N₃O₂
SMILES

COC1=CC=C(C=C1)CC(NC2=NNC(C3CCC3)=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Robb CM, et al.. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC). Chemical communications (Cambridge, England). 2017 Jul 04;53(54):7577-7580. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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CDK9 ligand 1

All CDK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CDK9 ligand 1 Related Classifications

HY-150889 Related Classifications