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Art. -Nr.: HY-150889

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CDK9 ligand 1

CDK9 ligand 1 is a CDK9-targeting ligand. CDK9 ligand 1 can be used for PROTAC synthesis, and serves as the target protein ligand for PROTAC CDK9 Degrader-1 (HY-103628).

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CAS. Nr.: 2118356-94-6
Formel: C₁₆H₁₉N₃O₂
Molecular Weight:285.34

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK9 ligand 1 Chemical Structure

CAS. Nr.: 2118356-94-6

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

CDK9 ligand 1 is a CDK9-targeting ligand. CDK9 ligand 1 can be used for PROTAC synthesis, and serves as the target protein ligand for PROTAC CDK9 Degrader-1 (HY-103628)^[1].

IC₅₀ & Target^[1]

CDK9

Alle CDK Isoform-spezifische Produkte anzeigen :

In Vitro

CDK9 ligand 1 serves as the target protein ligand for PROTAC CDK9 Degrader-1 (HY-103628), which degrades CDK9 in a dose-dependent manner in HCT116 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2118356-94-6
Molecular Weight 285.34
Formel C₁₆H₁₉N₃O₂
SMILES

COC1=CC=C(C=C1)CC(NC2=NNC(C3CCC3)=C2)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Robb CM, et al.. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC). Chemical communications (Cambridge, England). 2017 Jul 04;53(54):7577-7580. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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CDK9 ligand 1

Alle CDK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

CDK9 ligand 1 Related Classifications

HY-150889 Related Classifications