CDK2-IN-27
CDK2-IN-27 (compound 1) is a potent CDK2 inhibitor with IC50 values of <10, >10-20 nM for CDK2/cyclin E1, CDK2/cyclin B1, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2927473-94-5
- Formula: C18H21N7O2
- Molecular Weight:367.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
CDK2/cyclin E1 <10 nM (IC50) |
CDK1/cyclinB1 >10-20 nM nM (IC50) |
Chemical Information
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CAS No. 2927473-94-5
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Molecular Weight 367.41
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Formula C18H21N7O2
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SMILES
CC1(CC1)NC(O[C@H](CC2)C[C@H]2C3=CC(NC4=NC=C(C#N)N=C4)=NN3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK2-IN-27 Related Classifications
HY-160643 Related Classifications
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