27589-33-9
27589-33-9
Chemical Structure
Azosemide
- CAS No.: 27589-33-9
- Formula:C12H11ClN6O2S2
- Molecular Weight:370.84
IUPAC Name: 2-chloro-5-(1H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
InChIKey: HMEDEBAJARCKCT-UHFFFAOYSA-N
SMILES: ClC1=CC(NCC2=CC=CS2)=C(C3=NN=NN3)C=C1S(N)(=O)=O
Biological Activity: Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246 μM and 0.197 μM for hNKCC1A and NKCC1B, respectively[1].
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Azosemide | 99.85% | Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246 μM and 0.197 μM for hNKCC1A and NKCC1B, respectively. | ||||||||||||||||||||
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Azosemide (Standard) | ≥98% | Azosemide (Standard) is the analytical standard of Azosemide. This product is intended for research and analytical applications. Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246 μM and 0.197 μM for hNKCC1A and NKCC1B, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.57
HY-B0135Furosemide -
Similarity Score 0.57
HY-157578COX-2-IN-38 -
Similarity Score 0.57
HY-B0135AFurosemide sodium -
Similarity Score 0.56
HY-152105Metallo-β-lactamase-IN-9 -
Similarity Score 0.55
HY-W208353Furosemide impurity 1 -
Similarity Score 0.55
HY-151973Xanthine oxidoreductase-IN-3 -
Similarity Score 0.54
HY-126179RFenquizone (Standard) -
Similarity Score 0.53
HY-151974Xanthine oxidoreductase-IN-4 -
Similarity Score 0.52
HY-147816Anticancer agent 70 -
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