2770263-77-7
2770263-77-7
Chemical Structure
SZUH280
- CAS No.: 2770263-77-7
- Formula:C36H34N8O8
- Molecular Weight:706.70
InChIKey: OCXICBCMNKOWFI-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C(N(C=C2)CC3=CC=C(C=C3)OCCOCCN4C=C(N=N4)CNC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=C1)NO
Biological Activity: SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC50 of 0.58 μM in A549 cells. SZUH280 induces cancer cell apoptosis. SZUH280 hampers DNA damage repair in cancer cells, promoting cellular radiosensitization[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SZUH280 | 99.38% | SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC50 of 0.58 μM in A549 cells. SZUH280 induces cancer cell apoptosis. SZUH280 hampers DNA damage repair in cancer cells, promoting cellular radiosensitization. | ||||||||||||||||||||
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References
Keywords
