2815296-08-1
2815296-08-1
Chemical Structure
CVN293
- CAS No.: 2815296-08-1
- Formula:C14H10FN7O
- Molecular Weight:311.27
InChIKey: ONRXHVJHFORDDI-UHFFFAOYSA-N
SMILES: NC1=NON=C1C2=NC3=CC=CC(F)=C3N2CC4=NN=CC=C4
Biological Activity: CVN293 is a selective and brain permeable potassium ion (K+) channel KCNK13 inhibtor with IC50s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively. CVN293 potently inhibits the NLRP3-inflammasome mediated production of the proinflammatory cytokine IL-1β in microglia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CVN293 | 99.91% | CVN293 is a selective and brain permeable potassium ion (K+) channel KCNK13 inhibtor with IC50s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively. CVN293 potently inhibits the NLRP3-inflammasome mediated production of the proinflammatory cytokine IL-1β in microglia. | ||||||||||||||||||||
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References
Keywords
