286930-02-7
286930-02-7
Chemical Structure
Fesoterodine
- CAS No.: 286930-02-7
- Formula:C26H37NO3
- Molecular Weight:411.58
IUPAC Name: (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl isobutyrate
InChIKey: DCCSDBARQIPTGU-HSZRJFAPSA-N
SMILES: O=C(C(C)C)OC1=CC=C(CO)C=C1[C@@H](C2=CC=CC=C2)CCN(C(C)C)C(C)C
Biological Activity: Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fesoterodine | 99.61% | Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB). | ||||||||||||||||||||
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rac-Fesoterodine-d14 fumarate | (Rac)-Fesoterodine-d14 fumarate is a labelled racemic Fesoterodine. Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKivalues of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB). | |||||||||||||||||||||
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Fesoterodine-d3 | Fesoterodine-d3 is the deuterium labeled Fesoterodine (HY-70053). Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB). | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-A0030RFesoterodine fumarate (Standard) -
Similarity Score 0.85
HY-180471Desisopropyl-fesoterodine -
Similarity Score 0.79
HY-70053AFesoterodine L-mandelate -
Similarity Score 0.77
HY-76570A(Rac)-5-Hydroxymethyl Tolterodine hydrochloride -
Similarity Score 0.76
HY-76569RDesfesoterodine (Standard) -
Similarity Score 0.76
HY-76570(Rac)-5-Hydroxymethyl Tolterodine -
Similarity Score 0.76
HY-76996Tolterodine impurity 1 -
Similarity Score 0.76
HY-43452SFesoterodine-d7 hydrochloride -
Similarity Score 0.76
HY-76569B5-Hydroxymethyl tolterodine formate -
Explore the MedChemAI to find more analogs
References
- [1]. Ellsworth P, et al. Fesoterodine for the treatment of urinary incontinence and overactive bladder. Ther Clin Risk Manag. 2009;5:869-76. Epub 2009 Nov 18. [Content Brief]
- [2]. Didem Yilmaz-Oral, et al. The Beneficial Effect of Fesoterodine, a Competitive Muscarinic Receptor Antagonist on Erectile Dysfunction in Streptozotocin-induced Diabetic Rats [Content Brief]
