2870-71-5
Chemical Structure
Atropine methyl bromide
Synonym(s): Methylatropine bromide
- CAS No.: 2870-71-5
- Formula:C18H26BrNO3
- Molecular Weight:384.31
IUPAC Name: (1R,3r,5S)-3-((3-hydroxy-2-phenylpropanoyl)oxy)-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide
InChIKey: XMLNCADGRIEXPK-KUMOIWDRSA-M
SMILES: C[N+]1([C@H]2C[C@H](OC(C(C3=CC=CC=C3)CO)=O)C[C@@H]1CC2)C.[Br-]
Biological Activity: Atropine methyl bromide (Methylatropine bromide), an antagonist of muscarinic acetylcholine receptors (mAChR), is a quaternary ammonium salt of atropine and an active molecule used for pupil dilation during ophthalmic examinations. Due to its high polarity, it is used to relieve pyloric spasm in infants. It is less likely than atropine to cross the central nervous system[1][2].
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Atropine methyl bromide | 99.84% | Atropine methyl bromide (Methylatropine bromide), an antagonist of muscarinic acetylcholine receptors (mAChR), is a quaternary ammonium salt of atropine and an active molecule used for pupil dilation during ophthalmic examinations. Due to its high polarity, it is used to relieve pyloric spasm in infants. It is less likely than atropine to cross the central nervous system. | ||||||||||||||||||||
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Atropine methyl bromide (Standard) | ≥98% | Atropine methyl bromide (Standard) is the analytical standard of Atropine methyl bromide. This product is intended for research and analytical applications. Atropine methyl bromide (Methylatropine bromide), an antagonist of muscarinic acetylcholine receptors (mAChR), is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine. | ||||||||||||||||||||
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Similarity Score 0.92
HY-112076AAtropine methyl nitrate -
Similarity Score 0.89
HY-122510Atropine oxide -
Similarity Score 0.88
HY-122510AAtropine oxide hydrochloride -
Similarity Score 0.86
HY-B0241Ipratropium bromide -
Similarity Score 0.86
HY-B1388Homatropine (methylbromide) -
Similarity Score 0.85
HY-B1332Ipratropium bromide hydrate -
Similarity Score 0.83
HY-B1205BAtropine hydrobromide -
Similarity Score 0.83
HY-N0471BL-Hyoscyamine hydrobromide -
Similarity Score 0.83
HY-B1205Atropine -
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References
- [1]. Che MM, et al. Post-exposure treatment with nasal atropine methyl bromide protects against microinstillation inhalation exposure to sarin in guinea pigs. Toxicol Appl Pharmacol. 2009;239(3):251-257. [Content Brief]
- [2]. Khavari KA, et al. Atropine and atropine methyl bromide effects on behavior of rats. Int J Neuropharmacol. 1967 Jul;6(4):301-6. [Content Brief]
