2883540-91-6
2883540-91-6
Chemical Structure
(S)-Tersolisib
Synonym(s): (S)-STX-478;(S)-STX-478-101;(S)-LY4064809
- CAS No.: 2883540-91-6
- Formula:C16H12F5N5O2
- Molecular Weight:401.29
InChIKey: LGPNQALKGDDVBD-ZDUSSCGKSA-N
SMILES: NC1=NC=C(C=N1)NC(N[C@@H](C2=C(C3=CC(F)=CC(F)=C3O2)C)C(F)(F)F)=O
Biological Activity: (S)-STX-478 is the S-enantiomer of STX-478. STX-478 is a selective inhibitor of PI3Kα mutants, preventing metabolic dysfunction and demonstrating antitumor activity in xenograft mouse models with PI3Kα mutant tumors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S)-Tersolisib | 99.18% | (S)-STX-478 is the S-enantiomer of STX-478. STX-478 is a selective inhibitor of PI3Kα mutants, preventing metabolic dysfunction and demonstrating antitumor activity in xenograft mouse models with PI3Kα mutant tumors. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-156681Tersolisib -
Similarity Score 0.58
HY-183285PI3Kα-IN-32 -
Similarity Score 0.45
HY-76612SB-408124 Hydrochloride -
Similarity Score 0.44
HY-70068RSB-408124 (Standard) -
Similarity Score 0.43
HY-12572TIE-2/VEGFR-2 kinase-IN-2 -
Similarity Score 0.43
HY-163616Anticancer agent 221 -
Similarity Score 0.43
HY-179609C201-0243 -
Similarity Score 0.42
HY-151435CCR6 antagonist 1 -
Similarity Score 0.42
HY-184882NLRP3-IN-95 -
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