29106-51-2
Chemical Structure
Procyanidol B4
Synonym(s): (-)-Procyanidin B4
- CAS No.: 29106-51-2
- Formula:C30H26O12
- Molecular Weight:578.52
IUPAC Name: (2R,2'R,3S,3'R,4S)-2,2'-bis(3,4-dihydroxyphenyl)-[4,8'-bichromane]-3,3',5,5',7,7'-hexaol
InChIKey: XFZJEEAOWLFHDH-VUGKQVTMSA-N
SMILES: O[C@H]1[C@H](C2=C3C(C[C@@H](O)[C@@H](C4=CC(O)=C(O)C=C4)O3)=C(O)C=C2O)C5=C(O)C=C(O)C=C5O[C@@H]1C6=CC(O)=C(O)C=C6
Biological Activity: Procyanidol B4 ((-)-Procyanidin B4) is an orally active polyphenol found in Q.gilva. Procyanidol B4 exerts antioxidant activity by scavenging DPPH (HY-112053) (IC50: 12.15 μM) and Nitro blue tetrazolium chloride (NBT) (HY-15925) (IC50: 8.67 μM). Procyanidol B4 exhibits anti-inflammatory activity by inhibiting the expression of COX-2 and IL-1β and iNOS[1][2].
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Procyanidol B4 | 99.99% | Procyanidol B4 ((-)-Procyanidin B4) is an orally active polyphenol found in Q.gilva. Procyanidol B4 exerts antioxidant activity by scavenging DPPH (HY-112053) (IC50: 12.15 μM) and Nitro blue tetrazolium chloride (NBT) (HY-15925) (IC50: 8.67 μM). Procyanidol B4 exhibits anti-inflammatory activity by inhibiting the expression of COX-2 and IL-1β and iNOS. | ||||||||||||||||||||
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Procyanidol B4 (Standard) | ≥98% | Procyanidol B4 (Standard) is the analytical standard of Procyanidol B4 (HY-107208). This product is intended for research and analytical applications. Procyanidol B4 ((-)-Procyanidin B4) is an orally active polyphenol found in Q.gilva. Procyanidol B4 exerts antioxidant activity by scavenging DPPH (HY-112053) (IC50: 12.15 μM) and Nitro blue tetrazolium chloride (NBT) (HY-15925) (IC50: 8.67 μM). Procyanidol B4 exhibits anti-inflammatory activity by inhibiting the expression of COX-2 and IL-1β and iNOS . | ||||||||||||||||||||
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Similarity Score 1.00
HY-N0795Procyanidin B1 -
Similarity Score 1.00
HY-N0796Procyanidin B2 -
Similarity Score 1.00
HY-N2345RProcyanidin B3 (Standard) -
Similarity Score 0.91
HY-W714933Prodelphinidin B3 -
Similarity Score 0.90
HY-N7935Procyanidin B5 -
Similarity Score 0.88
HY-174260Neuroprotective agent 11 -
Similarity Score 0.81
HY-138213Afzelechin-(4α→8)-epiafzelechin -
Similarity Score 0.77
HY-N2342RProcyanidin C1 (Standard) -
Similarity Score 0.77
HY-N7521Procyanidin C2 -
Explore the MedChemAI to find more analogs
References
- [1]. Youn SH, et al. Anti-Inflammatory and Anti-Urolithiasis Effects of Polyphenolic Compounds from Quercus gilva Blume. Molecules. 2017 Jul 5;22(7):1121. [Content Brief]
- [2]. Bittner K, et al. Systemic absorption and metabolism of dietary procyanidin B4 in pigs. Mol Nutr Food Res. 2014 Dec;58(12):2261-73. [Content Brief]
