2914879-10-8
2914879-10-8
Chemical Structure
KIF18A-IN-6
- CAS No.: 2914879-10-8
- Formula:C28H37N3O5S2
- Molecular Weight:559.74
IUPAC Name: N-(tert-butyl)-3-(5''-(ethylsulfonamido)dispiro[cyclopropane-1,1'-cyclohexane-4',3''-indoline]-1''-carbonyl)benzenesulfonamide
InChIKey: AXRRVVWONHGXHG-UHFFFAOYSA-N
SMILES: O=S(C1=CC(C(N2CC3(CCC4(CC4)CC3)C5=CC(NS(CC)(=O)=O)=CC=C52)=O)=CC=C1)(NC(C)(C)C)=O
Biological Activity: KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor with an IC50 of 0.016 μM against KIF18A microtubule-dependent ATPase activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KIF18A-IN-6 | 98.48% | KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor with an IC50 of 0.016 μM against KIF18A microtubule-dependent ATPase activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.93
HY-153066VLS-1272 -
Similarity Score 0.60
HY-145803KIF18A-IN-3 -
Similarity Score 0.58
HY-145802KIF18A-IN-2 -
Similarity Score 0.55
HY-145034KIF18A-IN-1 -
Similarity Score 0.47
HY-144894AM-5308 -
Similarity Score 0.47
HY-111273AR244555 -
Similarity Score 0.47
HY-151876Glucocorticoid receptor modulator 1 -
Similarity Score 0.46
HY-18344Satavaptan -
Similarity Score 0.46
HY-162937KIF18A-IN-13 -
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