2920064-17-9
Chemical Structure
STING-IN-5
- CAS No.: 2920064-17-9
- Formula:C47H67NO9S2
- Molecular Weight:854.17
IUPAC Name: benzyl (E)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-3-((3-((3-((allyloxy)amino)-3-oxopropyl)disulfanyl)propanoyl)oxy)-11-hydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoate
InChIKey: UBXHZHGRHRYYRQ-KBRRQLEJSA-N
SMILES: C[C@H]([C@H](OC(CCSSCCC(NOCC=C)=O)=O)CC[C@@]1([C@@]2([C@@H](C[C@]3(/C4=C(CC/C=C(C)/C)\C(OCC5=CC=CC=C5)=O)[H])O)[H])C)[C@@]1(CC[C@]2(C)[C@@]3(C)C[C@@H]4OC(C)=O)[H]
Biological Activity: STING-IN-5 is a potent STING inhibitor, inhibiting LPS-induced NO synthesis in macrophages with an IC50 value of 1.15 μM. STING-IN-5 inhibits the inflammatory response. STING-IN-5 can be used to research anti-inflammatory diseases and sepsis[1].
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STING-IN-5 | 99.89% | STING-IN-5 is a potent STING inhibitor, inhibiting LPS-induced NO synthesis in macrophages with an IC50 value of 1.15 μM. STING-IN-5 inhibits the inflammatory response. STING-IN-5 can be used to research anti-inflammatory diseases and sepsis. | ||||||||||||||||||||
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Keywords