2945204-95-3
2945204-95-3
Chemical Structure
JAK1-IN-12
- CAS No.: 2945204-95-3
- Formula:C20H23N5O
- Molecular Weight:349.43
InChIKey: GRNVQRLQIUHOOP-OUQJNZHLSA-N
SMILES: O[C@]12C[C@@H](C[C@H]3C2)[C@H](NC4=C(C=CN5)C5=NC=C4C6=CNN=C6)[C@@H](C3)C1
Biological Activity: JAK1-IN-12 is a selective inhibitor of JAK1, with IC50 of 0.0246 μM. And IC50s of 0.423 μM, 0.410 μM and 1.12 μM for JAK2, JAK3 and TYK2. JAK1-IN-12 promotes hair growth in mice. JAK1-IN-12 can be used for research of immune and inflammatory diseases[1].
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JAK1-IN-12 | JAK1-IN-12 is a selective inhibitor of JAK1, with IC50 of 0.0246 μM. And IC50s of 0.423 μM, 0.410 μM and 1.12 μM for JAK2, JAK3 and TYK2. JAK1-IN-12 promotes hair growth in mice. JAK1-IN-12 can be used for research of immune and inflammatory diseases. | |||||||||||||||||||||
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