2951007-81-9
2951007-81-9
Chemical Structure
ATM Inhibitor-9
- CAS No.: 2951007-81-9
- Formula:C25H32N6O2
- Molecular Weight:448.56
InChIKey: PEGCDTKIRKSHBF-UHFFFAOYSA-N
SMILES: O=C(NC1=NC2=CC(C3=CC=C(N=C3)OCCCN(C)C)=CC=C2N=C1)NC4CCCCC4
Biological Activity: ATM Inhibitor-9 (Compd 7a) is a potent ATM inhibitor with IC505 nM for ATM kinase, useful in cancer research[1].
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ATM Inhibitor-9 | ATM Inhibitor-9 (Compd 7a) is a potent ATM inhibitor with IC505 nM for ATM kinase, useful in cancer research. | |||||||||||||||||||||
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References
- [1]. Dexin Deng, et al. Discovery and Evaluation of 3-Quinoxalin Urea Derivatives as Potent, Selective, and Orally Available ATM Inhibitors Combined with Chemotherapy for the Treatment of Cancer via Goal-Oriented Molecule Generation and Virtual Screening. J Med Chem. 2023 Jul 27;66(14):9495-9518. [Content Brief]
