3007772-60-0
Chemical Structure
ABD957
- CAS No.: 3007772-60-0
- Formula:C27H36F3N7O5S
- Molecular Weight:627.68
IUPAC Name: 2-(8-(2-(((S)-4-(3-(N,N-dimethylsulfamoyl)-1H-pyrazole-1-carbonyl)-3-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)-3,8-diazabicyclo[3.2.1]octan-3-yl)acetic acid
InChIKey: ISNXAOFEMNFJCO-XTWGIRIWSA-N
SMILES: C[C@H]1CN(CCN1C(N2C=CC(S(=O)(N(C)C)=O)=N2)=O)CC3=C(C=C(C=C3)C(F)(F)F)N4C5CCC4CN(C5)CC(O)=O
Biological Activity: ABD957 is a potent and selective covalent inhibitor of the ABHD17 family of depalmitoylases, with an IC50 of 0.21 μM for ABHD17B. ABD957 can block N-Ras signaling and the growth of NRAS-mutant AML cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ABD957 | 98.14% | ABD957 is a potent and selective covalent inhibitor of the ABHD17 family of depalmitoylases, with an IC50 of 0.21 μM for ABHD17B. ABD957 can block N-Ras signaling and the growth of NRAS-mutant AML cells. | ||||||||||||||||||||
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Keywords
