3033697-91-2
3033697-91-2
Chemical Structure
ZIKV-IN-4
- CAS No.: 3033697-91-2
- Formula:C33H37NO4
- Molecular Weight:511.65
IUPAC Name: 3-((E)-2-((1R,4aS,5S,8aR,E)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-6-(hydroxyimino)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)vinyl)furan-2(5H)-one
InChIKey: CNJXJQYXVDCGSC-IBXYCOHGSA-N
SMILES: C=C(CC[C@]1([H])[C@@]/2(COC(C3=CC=CC=C3)C4=CC=CC=C4)C)[C@@H](/C=C/C5=CCOC5=O)[C@]1(C)CCC2=N/O
Biological Activity: ZIKV-IN-4 (compound 5b) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=3.49 μM). ZIKV-IN-4 effectively inhibits the activity of ZIKV NS5 MTase[1].
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ZIKV-IN-4 | ZIKV-IN-4 (compound 5b) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=3.49 μM). ZIKV-IN-4 effectively inhibits the activity of ZIKV NS5 MTase. | |||||||||||||||||||||
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References
Keywords
