3036604-59-5
3036604-59-5
Chemical Structure
CDK2 degrader 1
- No. CAS: 3036604-59-5
- Formula:C23H27F2N3O4
- Molecular Weight:447.47
InChIKey: KUTYUVCSHRYCRH-QYCFJQJSSA-N
SMILES: [H][C@](C1)(CC2)C[C@]2([H])[C@@H]1COC(NC3CN(C4=CC(F)=C(C5C(NC(CC5)=O)=O)C(F)=C4)C3)=O
Biological Activity: CDK2 degrader 1 is a selective CDK2 molecular glue degrader. CDK2 degrader 1 binds to cereblon, induces ubiquitination of CDK2 and subsequent degradation via the proteasomal pathway. CDK2 degrader 1 is applicable for cancer-related research[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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CDK2 degrader 1 | 99.74% | CDK2 degrader 1 is a selective CDK2 molecular glue degrader. CDK2 degrader 1 binds to cereblon, induces ubiquitination of CDK2 and subsequent degradation via the proteasomal pathway. CDK2 degrader 1 is applicable for cancer-related research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.65
HY-170058CRBN ligand-12 -
Similarity Score 0.63
HY-W9982903-(2,6-Difluoro-4-(4-(2-hydroxyethyl)piperidin-1-yl)phenyl)piperidine-2,6-dione -
Similarity Score 0.54
HY-W1008865CRBN ligand-616 -
Similarity Score 0.53
HY-W1008737CRBN ligand-234 -
Similarity Score 0.52
HY-W1008876CRBN ligand-686 -
Similarity Score 0.52
HY-W440247CRBN ligand-109 -
Similarity Score 0.50
HY-W1008864CRBN ligand-231 -
Similarity Score 0.49
HY-W1008869CRBN ligand-684 -
Similarity Score 0.49
HY-W1008861CRBN ligand-615 -
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