CRBN ligand-686
CRBN ligand-686 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-686 can be linked to a target protein ligand via a linker to form a PROTAC.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3031608-38-2
- 分子式: C20H26FN3O2
- 分子量:359.45
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
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Cereblon |
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3031608-38-2
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分子量 359.45
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分子式 C20H26FN3O2
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SMILES
O=C1NC(=O)C(C2=CC=C(C=C2F)N3CCC4(CCNCC4)CC3)CC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)