3037847-72-3
3037847-72-3
Chemical Structure
FXR agonist 3
- CAS No.: 3037847-72-3
- Formula:C28H28BrNO4
- Molecular Weight:522.43
IUPAC Name: 5-(3,4-dichlorophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid
InChIKey: ZJDFWYFAYRTEHX-UHFFFAOYSA-M
SMILES: COC1=C(C=C2C(CC[N+]3=C2C=C4C=CC(OC)=C(C4=C3)OCC5=CC(C)=CC=C5)=C1)OC.[Br-]
Biological Activity: FXR agonist 3 is an anti-NASH agent, acting by activating FXR. FXR agonist 3 inhibits COL1A1, TGF-β1, α-SMA and TIMP1 expression with anti-fibrogenic activity. FXR agonist 3 significantly reduces liver steatosis and inflammation, improves liver fibrosis level[1].
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FXR agonist 3 | 96.51% | FXR agonist 3 is an anti-NASH agent, acting by activating FXR. FXR agonist 3 inhibits COL1A1, TGF-β1, α-SMA and TIMP1 expression with anti-fibrogenic activity. FXR agonist 3 significantly reduces liver steatosis and inflammation, improves liver fibrosis level. | ||||||||||||||||||||
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