308293-08-5
308293-08-5
Chemical Structure
SARS-CoV-2-IN-120
- CAS 番号: 308293-08-5
- Formula:C21H18N4O3S2
- Molecular Weight:438.52
InChIKey: HJZPZKJJQGFFBQ-UHFFFAOYSA-N
SMILES: CCC1=NN=C(S1)NS(=O)(C2=CC=C(C=C2)NC(C3=CC=CC4=CC=CC=C43)=O)=O
Biological Activity: SARS-CoV-2-IN-120 (Compound S22) is a SARS-CoV-2-specific entry inhibitor. SARS-CoV-2-IN-120 binds and trimerizes within the apex cavity of the SARS2 spike trimer. SARS-CoV-2-IN-120 blocks RBD-ACE2 interaction. SARS-CoV-2-IN-120 neutralizes BA.2 and subsequent Omicron variants. SARS-CoV-2-IN-120 inhibits SARS-CoV-2 replication in mice[1].
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SARS-CoV-2-IN-120 | SARS-CoV-2-IN-120 (Compound S22) is a SARS-CoV-2-specific entry inhibitor. SARS-CoV-2-IN-120 binds and trimerizes within the apex cavity of the SARS2 spike trimer. SARS-CoV-2-IN-120 blocks RBD-ACE2 interaction. SARS-CoV-2-IN-120 neutralizes BA.2 and subsequent Omicron variants. SARS-CoV-2-IN-120 inhibits SARS-CoV-2 replication in mice. | |||||||||||||||||||||
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References
Keywords
