3109709-80-7

Gemcitabine-O-Si(di-iso)-O-Mc Chemical Structure
3109709-80-7

Chemical Structure

Gemcitabine-O-Si(di-iso)-O-Mc

  • CAS No.: 3109709-80-7
  • Formula:C24H36F2N4O7Si
  • Molecular Weight:558.65

IUPAC Name: 1-(5-(((((2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methoxy)diisopropylsilyl)oxy)pentyl)-1H-pyrrole-2,5-dione

InChIKey: UANWPSOXUYWBLM-ZPMCFJSWSA-N

SMILES: NC(C=CN1[C@H]2C(F)([C@@H]([C@H](O2)CO[Si](C(C)C)(OCCCCCN3C(C=CC3=O)=O)C(C)C)O)F)=NC1=O

Biological Activity: Gemcitabine-O-Si(di-iso)-O-Mc is a agent-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker[1].

Cat. No. Product Name Purity Description Pricing
HY-130812
Gemcitabine-O-Si(di-iso)-O-Mc 98.82% Gemcitabine-O-Si(di-iso)-O-Mc is a agent-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References