31356-95-3
Chemical Structure
8-OH-cAMP
Synonym(s): 8-Hydroxy-cAMP
- CAS No.: 31356-95-3
- Formula:C10H12N5O7P
- Molecular Weight:345.21
IUPAC Name: (4aR,6R,7R,7aS)-6-(6-amino-8-hydroxy-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide
InChIKey: WCMOKPQGYXJAFO-UUOKFMHZSA-N
SMILES: O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C(O)=NC4=C3N=CN=C4N
Biological Activity: 8-OH-cAMP (8-Hydroxy-cAMP) is a polar, membrane-impermeable cyclic adenosine monophosphate analog that is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. As a polar PKA agonist, 8-OH-cAMP is used to study the role of cAMP in the development and progression of cardiovascular and metabolic diseases[1].
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8-OH-cAMP | 8-OH-cAMP (8-Hydroxy-cAMP) is a polar, membrane-impermeable cyclic adenosine monophosphate analog that is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. As a polar PKA agonist, 8-OH-cAMP is used to study the role of cAMP in the development and progression of cardiovascular and metabolic diseases. | |||||||||||||||||||||
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Keywords
