314291-83-3

PHPS1 Chemical Structure
314291-83-3

Chemical Structure

PHPS1

  • CAS No.: 314291-83-3
  • Formula:C21H15N5O6S
  • Molecular Weight:465.44

IUPAC Name: (E)-4-(2-(3-(4-nitrophenyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)benzenesulfonic acid

InChIKey: VIQSBJOMLQLAKC-BSYVCWPDSA-N

SMILES: O=S(C1=CC=C(N/N=C2C(C3=CC=C([N+]([O-])=O)C=C3)=NN(C4=CC=CC=C4)C\2=O)C=C1)(O)=O

Biological Activity: PHPS1 is a potent and selective Shp2 inhibitor with Kis of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-112368
PHPS1 98.99% PHPS1 is a potent and selective Shp2 inhibitor with Kis of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively.
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