314291-83-3

PHPS1 Chemical Structure
314291-83-3

Chemical Structure

PHPS1

  • CAS No.: 314291-83-3
  • Formula:C21H15N5O6S
  • Molecular Weight:465.44

IUPAC Name: (E)-4-(2-(3-(4-nitrophenyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)benzenesulfonic acid

InChIKey: VIQSBJOMLQLAKC-BSYVCWPDSA-N

SMILES: O=S(C1=CC=C(N/N=C2C(C3=CC=C([N+]([O-])=O)C=C3)=NN(C4=CC=CC=C4)C\2=O)C=C1)(O)=O

Biological Activity: PHPS1 is a potent and selective Shp2 inhibitor with Kis of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-112368
PHPS1 98.99% PHPS1 is a potent and selective Shp2 inhibitor with Kis of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References