334949-59-6
334949-59-6
Chemical Structure
BIX02188
- CAS No.: 334949-59-6
- Formula:C25H24N4O2
- Molecular Weight:412.49
IUPAC Name: (Z)-3-(((3-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxamide
InChIKey: FSZPIAXLCCQFCM-FCQUAONHSA-N
SMILES: O=C(N)C1=CC(NC2=O)=C(/C2=C(C3=CC=CC=C3)/NC4=CC=CC(CN(C)C)=C4)C=C1
Biological Activity: BIX02188 is a potent MEK5-selective inhibitor with an IC50 of 4.3 nM. BIX02188 inhibits ERK5 catalytic activity, with an IC50 of 810 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BIX02188 | 98.10% | BIX02188 is a potent MEK5-selective inhibitor with an IC50 of 4.3 nM. BIX02188 inhibits ERK5 catalytic activity, with an IC50 of 810 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-107622(E/Z)-BIX02188 -
Similarity Score 0.92
HY-12202MEK inhibitor -
Similarity Score 0.90
HY-12056BIX02189 -
Similarity Score 0.90
HY-12056A(E/Z)-BIX02189 -
Similarity Score 0.80
HY-171878BI-4659 -
Similarity Score 0.74
HY-Z0013RNintedanib impurity 7 (Standard) -
Similarity Score 0.73
HY-18955BI-847325 -
Similarity Score 0.72
HY-Z4752Nintedanib impurity 3 -
Similarity Score 0.71
HY-13783BIBF0775 -
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