339103-05-8
339103-05-8
Chemical Structure
JY-2
- CAS No.: 339103-05-8
- Formula:C13H7Cl2N3O
- Molecular Weight:292.12
IUPAC Name: 5-(2,4-dichlorophenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole
InChIKey: WBMHQMQALJDGHI-UHFFFAOYSA-N
SMILES: ClC1=CC(Cl)=C(C2=NC(C3=CC=CC=N3)=NO2)C=C1
Biological Activity: JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
JY-2 | 99.75% | JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
