34552-83-5
34552-83-5
Chemical Structure
Loperamide hydrochloride
Synonym(s): R-18553 hydrochloride
- CAS No.: 34552-83-5
- Formula:C29H34Cl2N2O2
- Molecular Weight:513.50
IUPAC Name: 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride
InChIKey: PGYPOBZJRVSMDS-UHFFFAOYSA-N
SMILES: O=C(N(C)C)C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3.Cl
Biological Activity: Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist[1][2][3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect[4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Loperamide hydrochloride | 99.84% | Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect. | ||||||||||||||||||||
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Loperamide hydrochloride (Standard) | 99.89% | Loperamide (hydrochloride) (Standard) is the analytical standard of Loperamide (hydrochloride). This product is intended for research and analytical applications. Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect. | ||||||||||||||||||||
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Loperamide-d6 hydrochloride | 99.07% | Loperamide-d6 (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea. | ||||||||||||||||||||
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References
- [1]. Hanauer, S.B., The role of loperamide in gastrointestinal disorders. Rev Gastroenterol Disord, 2008. 8(1): p. 15-20. [Content Brief]
- [2]. Litovitz, T., et al., Surveillance of loperamide ingestions: an analysis of 216 poison center reports. J Toxicol Clin Toxicol, 1997. 35(1): p. 11-9. [Content Brief]
- [3]. http://www.drugs.com/mmx/loperamide-hydrochloride.html
- [4]. Hatfield MJ, et al. Carboxylesterase inhibitors. Expert Opin Ther Pat. 2011 Aug;21(8):1159-71. [Content Brief]
