351372-19-5
Chemical Structure
PD 0305970
- CAS No.: 351372-19-5
- Formula:C18H24FN5O2
- Molecular Weight:361.41
InChIKey: SMONLCFJGCJROJ-WDEREUQCSA-N
SMILES: CC1=C2N(C3CC3)C(N(C(C2=CC(F)=C1N4C[C@](CC4)([H])[C@@H](N)C)=O)N)=O
Biological Activity: PD 0305970 is an orally active bacterial gyrase and topoisomerase inhibitor. PD 0305970 shows exceptional activity against gram-positive and fastidious organisms and more modest activity against gram-negative species. PD 0305970 shows low spontaneous resistance frequencies. PD 0305970 shows antibacterial efficacy in murine streptococcal sepsis and pneumococcal pneumonia models. PD 0305970 can be used for the research of bacterial infection[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PD 0305970 | PD 0305970 is an orally active bacterial gyrase and topoisomerase inhibitor. PD 0305970 shows exceptional activity against gram-positive and fastidious organisms and more modest activity against gram-negative species. PD 0305970 shows low spontaneous resistance frequencies. PD 0305970 shows antibacterial efficacy in murine streptococcal sepsis and pneumococcal pneumonia models. PD 0305970 can be used for the research of bacterial infection. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Huband MD, et al. In vitro and in vivo activities of PD 0305970 and PD 0326448, new bacterial gyrase/topoisomerase inhibitors with potent antibacterial activities versus multidrug-resistant gram-positive and fastidious organism groups. Antimicrob Agents Chemother. 2007;51(4):1191-1201. [Content Brief]
Keywords
