35941-65-2
35941-65-2
Chemical Structure
Butriptyline
Synonym(s): Butriptylene
- CAS No.: 35941-65-2
- Formula:C21H27N
- Molecular Weight:293.45
IUPAC Name: 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N,2-trimethylpropan-1-amine
InChIKey: ALELTFCQZDXAMQ-UHFFFAOYSA-N
SMILES: CC(CN(C)C)CC1C2=CC=CC=C2CCC3=C1C=CC=C3
Biological Activity: Butriptyline (Butriptylene) is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. Butriptyline does not inhibit brain norepinephrine uptake. Butriptyline can be used for depression research[1][2][3].
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Butriptyline | Butriptyline (Butriptylene) is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. Butriptyline does not inhibit brain norepinephrine uptake. Butriptyline can be used for depression research. | |||||||||||||||||||||
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References
- [1]. Pugsley TA, et al. Effect of butriptyline on the brain uptake mechanisms for noradrenaline and 5-hydroxytryptamine. J Pharm Pharmacol. 1974 Oct;26(10):778-8. [Content Brief]
- [2]. Dulloo AG, et al. Screening of drugs for thermogenic anti-obesity properties: antidepressants. Ann Nutr Metab. 1987;31(2):69-80. [Content Brief]
- [3]. Molinengo L, et al. The action of imipramine, amitriptyline, doxepin and butriptyline in an operant conditioning schedule. Psychopharmacologia. 1972;24(2):247-57. [Content Brief]
Keywords
