36048-23-4
Chemical Structure
Dehydrodicatechin A
- CAS No.: 36048-23-4
- Formula:C30H24O12
- Molecular Weight:576.50
InChIKey: XNGZKGIFXTWBFN-LTVJOWCOSA-N
SMILES: O[C@@]12C[C@]3([C@]4([H])[C@@](CC5=C(O)C=C(O)C=C5O4)([H])O2)C(C6=C(O[C@H](C7=CC(O)=C(C=C7)O)[C@H](C8)O)C8=C(O)C=C6O3)=CC1=O
Biological Activity: Dehydrodicatechin A is a biflavan catechin dimer and antioxidant. Dehydrodicatechin A is isolated from the roots of Hagenia abyssinica, the stem bark of Choerospondias axillaries, the stems of Entada phaseoloides, and Calligonum comosum. Dehydrodicatechin A exhibits ABTS+ radical cation, DPPH, ABTS, and superoxide anion radical scavenging activities, as well as ferric reducing/antioxidant power. Dehydrodicatechin A inhibits Lipase. Dehydrodicatechin A is used in studies on polycystic ovary syndrome, Ehrlich ascites, and Doxorubicin (HY-15142)-induced cardiotoxicity[1][2][3][4][5][6][7][8].
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Dehydrodicatechin A | Dehydrodicatechin A is a biflavan catechin dimer and antioxidant. Dehydrodicatechin A is isolated from the roots of Hagenia abyssinica, the stem bark of Choerospondias axillaries, the stems of Entada phaseoloides, and Calligonum comosum. Dehydrodicatechin A exhibits ABTS+ radical cation, DPPH, ABTS, and superoxide anion radical scavenging activities, as well as ferric reducing/antioxidant power. Dehydrodicatechin A inhibits Lipase. Dehydrodicatechin A is used in studies on polycystic ovary syndrome, Ehrlich ascites, and Doxorubicin (HY-15142)-induced cardiotoxicity. | |||||||||||||||||||||
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References
- [1]. Fan M, et al. Antioxidant and anti-proliferative properties of Hagenia abyssinica roots and their potentially active components. Antioxidants. 2020 Feb 6;9(2):143.
- [2]. Bannour M, et al. Phenolic profiling and antioxidant capacity of Calligonum azel Maire, a Tunisian desert plant. Food research international (Ottawa, Ont.). 2017 Nov;101:148-154.
- [3]. Li CW, et al. One new and nine known flavonoids from Choerospondias axillaries and their in vitro antitumor, anti-hypoxia and antibacterial activities. Molecules (Basel, Switzerland). 2014 Dec 19;19(12):21363-77.
- [4]. Tahmasebi F, et al. Antioxidant effects of calligonum extract on ovarian tissue of PCO model: An experimental study. International journal of reproductive biomedicine. 2018 Oct;16(10):641-648.
- [5]. Jeon S Y, Imm J Y. Lipase inhibition and cholesterol-lowering activities of laccase-catalyzed catechin polymers[J]. Food Science and Biotechnology, 2014, 23(5): 1703-1707.
- [6]. Shalabi M, et al. Anticancer activity of Aloe vera and Calligonum comosum extracts separetely on hepatocellular carcinoma cells. Asian Pacific Journal of Tropical Biomedicine. 2015 May 1;5(5):375-81.
- [7]. Ashour OM, et al. Evaluation of the potential cardioprotective activity of some Saudi plants against doxorubicin toxicity. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2012;67(5-6):297-307.
- [8]. Dong Y, et al. Antioxidant phenolic compounds from the stems of Entada phaseoloides. Chemistry & biodiversity. 2012 Jan;9(1):68-79.