36067-72-8
36067-72-8
Chemical Structure
Azepexole dihydrochloride
Synonym(s): B-HT 933 dihydrochloride; Oxazoloazepin dihydrochloride
- CAS No.: 36067-72-8
- Formula:C9H17Cl2N3O
- Molecular Weight:254.16
IUPAC Name: 6-ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride
InChIKey: HBLPYIOKPJVFQW-UHFFFAOYSA-N
SMILES: NC(O1)=NC2=C1CCN(CC)CC2.[H]Cl.[H]Cl
Biological Activity: Azepexole (B-HT 933) dihydrochloride is a potent and selective alpha 2-adrenoceptor agonist with pKis of 8.3, 7.6, and 7.5 for α2A-, α2B- and α2C-adrenoceptor subtypes, resepctively[1]. Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions (IC50= 78.72 nM)[2].
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Azepexole dihydrochloride | Azepexole (B-HT 933) dihydrochloride is a potent and selective alpha 2-adrenoceptor agonist with pKis of 8.3, 7.6, and 7.5 for α2A-, α2B- and α2C-adrenoceptor subtypes, resepctively. Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions (IC50= 78.72 nM). | |||||||||||||||||||||
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